Apoptosis of Alcohol-Exposed Human Placental Cytotrophoblast Cells is Downstream of Intracellular Calcium Signaling
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چکیده
منابع مشابه
Purinergic receptor activation by agonist stimulation of Rb efflux from human placental cytotrophoblast cells in culture
BeWo cells derived from a choriocarcinoma have been extensively used as a model of placental trophoblast. There are several clones of the BeWo cell line. Authentication and characterisation of these cloned cell lines is important to ensure their identity and purity prior to use in research. In order to be classified as cytotrophoblasts, cells need to fulfil certain criteria including the expres...
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Diindolylmethane (DIM), derived from indole-3-carbinol in cruciferous vegetables, causes growth arrest and apoptosis of cancer cells in vitro. DIM also induces endoplasmic reticulum (ER) stress, and thapsigargin, a specific inhibitor of the sarcoplasmic reticulum/ER calcium-dependent ATPase, enhances this effect. We asked whether elevated cytosolic free calcium [Ca2+]i is required for cytotoxic...
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ژورنال
عنوان ژورنال: Alcoholism: Clinical and Experimental Research
سال: 2014
ISSN: 0145-6008
DOI: 10.1111/acer.12417